Peer reviewed articles
Tan, D., Gram, L. and Middelboe, M. 2014. Characterization of vibriophages and their interactions with the fish pathogen Vibrio anguillarum. Appl. Environ. Microbiol. 80 (10): 3128-3140
Prol Garcia, M.J., P.W.D’Alvise, A.M. Rygaard and L. Gram 2014. Biofilm formation is not a prerequisite for production of the antibacterial compound tropodithietic acid in Phaeobacter inhibens DSM17395. J. Appl. Microbiol 117:1592-1600
Rabe, P., Klapschinski. T.A., Brock, N.L., Citron, C.A., D’Alvise, P., Gram, L. and Dickschat, J.S. 2014. Synthesis and Bioactivity of Analogs of the Marine Antibiotic Tropodithietic Acid. Beilstein Journal of Organic Chemistry. Beilstein J. Org. Chem. 10:1796–1801
Tan, D., Dahl, A. and Middelboe M. (2015) Vibriophages differentially influence biofilm formation by Vibrio anguillarum strains. Applied and Environ. Microbiol. 81 (13):4489-4497.
Tan, D., Svenningsen, SL and Middelboe, M. (2015) Quorum sensing determines the choice of anti-phage defense strategy in Vibrio anguillarum. mBIO 6(3): 00627-1
Rasmussen, B.B, T. Grotkjær, P. W. D’Alvise, G. Yin, F. Zhang, R. Xu, B. Bunk, C. Spröer, M. Bentzon-Tilia and L. Gram 2016. Vibrio anguillarum is genetically and phenotypically unaffected by long-term continuous exposure to the antibacterial compound tropodithietic acid. Appl. Environ. Microbiol. 82:4802-4810
Grotkjær, T., P. D’Alvise, M. Bentzon-Tilia, K. Dierckens, P. Bossier and L. Gram 2016. Phaeobacter inhibens as probiotic bacteria in non-axenic Artemia and algae cultures. Aquaculture 462:64-69
Grotkjær, T., P. D’Alvise, N. Dourala, K.F. Nielsen and L. Gram 2016. Isolation of TDA-producing Phaeobacter strains from sea bass larval rearing units and their probiotic effect against pathogenic Vibrio spp. in Artemia cultures. System. Appl. Microbiol. 39:180-188
D’Alvise, P.W., C.B.W. Phippen, K.F. Nielsen and L. Gram 2016. Influence of iron on the production of the antibacterial compound tropodithietic acid and its non-inhibitory analog in Phaeobacter inhibens. Appl. Environ. Microbiol. 82:502-509
Rønneseth, A., P.W. D’Alvise, Ø. Tønnesen, G. Haugland, D. Castillo, T. Grotkjær, K. Engell-Sørensen, L. Nørremark, Ø. Bergh, H. I. Wergeland and L. Gram 2017. Comparative assessment of Vibrio virulence in marine fish larvae. J. Fish Dis.(in press) DOI: 10.1111/jfd.12612
Castillo, D., P.W D Alvise, R. Xu, F. Zhang. M. Middelboe and L. Gram 2017. Comparative genome analyses of Vibrio anguillarum strains reveal a link with pathogenicity traits. mSystems 2: e00001-17
Genome Announcements
Romero, J., Higuera, G. Gajardo, F., Castillo, D., Middelboe, M., Garcia, K., Ramirez, C., and Espejo, R. (2014) Complete genome sequence of Vibrio anguillarum phage CHOED successfully used for phage therapy in aquaculture" GenomeA 2 (4): e0009-14.
Castillo, D., P. D´Alvise, M. Middelboe, L. Gram, S. Liu, P. Kalatzis, C. Kokkari, and P. Katharios. 2015 Draft genome sequences of the fish pathogen Vibrio harveyi strains VH2 and VH5. Genome Announcements 3:e01062-15; doi:10.1128/genomeA.01062-15
Castillo, D., P. D Alvise, P. Kalatzis, C. Kokkari, M. Middelboe, L. Gram, S. Liu and P. Katharios. 2015. Draft genome sequences of Vibrio alginolyticus strains V1 and V2, opportunistic marine pathogens. Genome Announcements 3:e00729-15; doi:10.1128/genomeA.00729-15
Castillo, D., J. Woo Jun, P. D´Alvise, M. Middelboe, L. Gram, S. Liu, and P. Katharios 2015. Draft genome sequence of Vibrio parahaemolyticus VH3 isolated from aquaculture environment in Greece. Genome Announcements 3:e00731-15; doi:10.1128/genomeA.00731-15
Conference lectures
D’Alvise, P.W., S.Lillebø, H.Wergeland, K.F.Nielsen, Ø.Bergh and L.Gram. 2013. Control of bacterial disease in cultures of marine larvae and live feed organisms by a probiotic bacterium. Presentation at LARVI, Ghent, Belgium
Demeng, T. and M.Middelboe 2013. Phage KVP40 Enhance Biofilm Formation in Vibrio anguillarum (PF430-3). Oral presentation at International Biofilm Course, University of Copenhagen
Tan, D., Svenningsen, SL., Middelboe, M. Two alternating defense strategies: 1) Spatial refuge and 2) Quorum Sensing induced down-regulation of OmpK receptor. Poster at EMBO Meeting: Viruses of Microbes, Zurich 2014
Tan, D., Svenningsen, SL., Middelboe, M. Quorum sensing determines the choice of anti-phage defense strategy in Vibrio anguillarum. Poster at Bacterophages 2015 meeting. London.
Middelboe, M. Examination of phage resistance mechanisms in marine Vibrio anguillarum. Seminar at Coastal Pathogen Group, University of Exeter, UK. 2015
Middelboe, M. Phage-host interactions in marine fish pathogens. Seminar at Niels Bohr Institute, University of Copenhagen. 2015
Middelboe, M. Virus-bacteria interactions: Nanoscale processes with global scale implications. Seminar at Institute for Chemistry and Biology of the Marine Environment (ICBM), University Oldenburg, Germany, 2015
Castillo, D.: Distribution of prophage-encoded properties in Vibrios. Workshop on “Phage-Vibrio interactions”. Massachusetts Institute of Technology, 26-28 April 2016
Middelboe, M.: Phage-host interactions in fish pathogens: Examination of phage resistance. Workshop on “Phage-Vibrio interactions”. Massachusetts Institute of Technology, 26-28 April 2016
Kalatzis, P.: Phage control of Vibrio and development of resistance. Workshop on “Phage-Vibrio interactions”. Massachusetts Institute of Technology, 26-28 April 2016
Rørbo, N.: Genomic analysis of Vibriophages. Workshop on “Phage-Vibrio interactions”. Massachusetts Institute of Technology, 26-28 April 2016
Middelboe, Tan & Svenningsen: Anti-phage defense strategies in the marine fish pathogen Vibrio anguillarum. Aquatic Virus Workshop, Plymouth July 2016.
Middelboe, M.: Antiphage defense strategies in the fish pathogens Vibrio anguillarum and Flavobacterium psychrophilum: implications for the use of phages in disease control. EMBO conference: Viruses of Microbes. Liverpool, July 2016
Middelboe, M.: Use of phages for pathogen control in aquaculture. PHAGES Meeting, Oxford September 2016.
Posters
Grotkær, T., P.W. D'Alvise and L.Gram 2013. Use of Phaeobacter inhibens as a probiont targeting Vibrio in Artemia cultures. Poster at Danish Society for Microbiology Yearly Meeting, Copenhagen, Denmark.
Demeng, T., L.Gram and M.Middelboe 2013. Characterization of Vibriophages and Their Interactions with the Fish Pathogen Vibrio anguillarum. Poster presented at PhD day at the Department of Biology, University of Copenhagen